Department of Internal Medicine, Digestive Disease Center and Research Institute, SoonChunHyang University School of Medicine, Bucheon 14584, Korea. Department of Food Science and Nutrition, SoonChunHyang University Bucheon Hospital, Bucheon 14584, Korea. Department of Internal Medicine, Division of Gastroenterology and Hepatology, SoonChunHyang University School of Medicine, Seoul 04401, Korea. Department of Internal Medicine, Division of Gastroenterology and Hepatology, SoonChunHyang University School of Medicine, Cheonan 31151, Korea. Clinical Trial Center, Department of Biostatistics, SoonChunHyang University Bucheon Hospital, Bucheon 14584, Korea.